f88-4 cys5 cyclic peptide phage display library (15-mer)
Cell Origins provides researchers with critical phage-based laboratory services and kits. We focus on the use of filamentous phage as an inexpensive, reliable, highly stable, and effective replacement for many products currently on the market.
Complete page context
The f88-4 cys5 cyclic 15-mer peptide phage display library is built from the
f88-4 filamentous phage vector (AF218363.1) by replacing a synthetic 21 bp stuffer sequence with frame-restoring 45 bp random oligo nucleotides. The resulting phage particles express the wild-type gene VIII and an artificial gene rVIII. The 15-mer foreign peptide insert is expressed on rVIII. The expressed peptides contains cysteines at positions 5 and 11 (XXXXCXXXXXCXXXX) constraining the peptide in a cyclic conformation under oxidative conditions. The f88-4 phage display libraries maintain
E. coli infectivity and do not require a helper phage for assembly and release of virions.
Product Specifications
SnapGene Image Full sequence
Please Cite
The original f88-4 15-mer peptide phage display library was created by Dr. George Smith at the University of Missouri and is distributed by Cell Origins (#COPD0004).
References section:
Scott JK, Smith GP. Searching for peptide ligands with an epitope library. Science. 1990 Jul 27;249(4967):386-90. doi: 10.1126/science.1696028.